Our research group is interested in understanding how chondrocyte-extracellular matrix interactions regulate homeostasis in the tissues of the temporomandibular joint. We are particularly interested in understanding the interaction of tissue mechanics and cell-matrix derived signaling. To study this complex interaction, we approach the problem at multiple scales. We have ongoing projects investigating the impact of full joint kinematics on lesion formation and tissue contact stresses, the biotribology of superficial layer articular cartilage, and the resulting changes in cell-matrix interactions.


David Reed, Reed Lab, The University of Illinois at Chicago (2015)